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December 8, NASA: Life with arsenic December 7, Last week, in a much publicized news conference, NASA announced the discovery of a bacterium that can use arsenic instead of phosphorus.
The news media covered it with a flourish -- and produced much nonsense. The paper was posted at the Science magazine web site, so we can look at what was really shown.
Whatever the hype that the news media added, it is an interesting -- but incomplete -- story. The figure at left shows a key experiment; this is Figure 1B of the paper. The graph shows the growth of the bacteria under different conditions. Number of cells on the y-axis log scale ; time on the x-axis.
The three conditions are, from the top: Importantly, if there is no addition, the bacteria grow very little, if at all lower curve. Then, arsenic in the form of arsenate does indeed stimulate growth middle curve.
So does phosphate; in fact, it is better upper curve. The above experiment along with other measurements does seem to establish the basic point: But now let's look at some of the limitations of the story -- as we have it so far. First, the bug prefers P to As: You can see this in the graph above.
They explicitly do not claim that the bug requires or prefers As, merely that it can use it.
Second and more importantly, the growth medium with no added P contains a trace level of P. This probably comes from low levels of P contaminating other chemicals they use. It's not enough to support growth alone lower curve in the graphbut it does mean that when the bugs are growing on As, they also have a small amount of P available.
In fact, analysis of the bacteria grown on As shows a weight ratio of about 7 As: On a mole basis, the ratio would be about half that. Thus there still is considerable P in the bacteria. They cannot claim a total replacement of As for P.
The paper recognizes this limitation, but some of the news coverage does not. This may be interesting, too. So, where is the As in the cell?
This becomes particularly important since the replacement is incomplete. And this is where the paper gets rather weak. They hand-wave that it is everywhere, but there is little specific information. Where did this bacterium come from?
It was isolated from Mono Lake -- a highly alkaline lake in the Sierras of eastern Californiawith a high As level. Thus it is likely that the starting bug was quite resistant to As. All the reported work was done under lab conditions.
There has been an opportunity for both physiological and genetic adaptation. Thus we do not know whether the bug uses As in nature. This does not minimize the importance of the work as a proof of principle.
It is whatever it is, and it could exist naturally. Did the "adaptation" to growing on As in the lab require genetic changes? There is not enough information given to tell. From what the paper said, the adaptation did not seem very difficult, so it is unlikely that extensive genetic changes were needed.
A concern about this work deals with the chemistry of As. It's true that As and P are in the same chemical family -- but family members are not identical.
Esters and anhydrides of arsenate are relatively unstable.Online Registration Now Closed - But Don't Worry You Can Register Onsite. For its sixth year, NCBiotech will convene ag tech investment firms, global ag tech companies and other key industry stakeholders for information sharing, networking and partnering.
Free Online Biology Multiple Choice Quizzes and practice tests for 5th grade, 7th Grade quiz, IGSCSE quiz, AP biology quiz, Sat biology quiz, NEET mcq, class 10 and 12 and all biology exams. At least one author of an abstract must be registered for the Congress in order to be included in the abstract book.
One author can present only ONE abstract. Its easy to write about what the government or other people should do with our/their money. It’s harder to come up with a course of action that I can undertake on my . ASSIGNMENT – 2 OF MGN SWOT Analysis of Idea Cellular Introduction of the company: | Idea cellular, a part of Aditya Birla group, is one of India’s leading GSM mobile services caninariojana.com telecom company has licenses to operate in all 22 service areas.
Presently it is operating in 13 circles. Ppt on idea cellular 1. MINI PROJECT ON IDEA CELLULAR Guide: U. Gangadhar Sir Trainee: M.
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